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Meditati

Smart drugs for mental health

Our mission is to cure addiction

Modern pharma is ultra-reductionist

Single-target philosophy is ineffective for discovering safe treatments for complex disorders like addiction.

Multitarget drug design is the future

All drugs are promiscuous. We design drugs with the help of AI that target multiple pathways for superior efficacy and safety.

Leadership

William Mangione

William Mangione

CEO

BrennanOverhoff

Brennan Overhoff

Zackary Falls

Zackary Falls

Matthew Muhoberac

Matthew Muhoberac

Gaurav Chopra

Gaurav Chopra

Ram Samudrala

Ram Samudrala

Pipeline

NCE Design
Early Discovery
Lead Optimization
Preclinical
IND-enabling
MED-01
Opioid use disorder
MED-02
Neuropathic pain

Media

News

June 4, 2025

Exploring the innovative, AI-powered CANDO drug discovery platform

Our team was featured in a recent article by the Clinical and Translational Science Institute at the University at Buffalo.

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June 5, 2024

AI Applications in Healthcare: The Next Frontier

Our CEO, William Mangione, spoke at a recent LifeScienceNY event in Albany about how AI is revolutionizing healthcare.

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February 21, 2023

2020 NCATS ASPIRE Reduction-to-Practice Challenge Winners

All of our founders were part of the winning team for developing solutions for the opioid crisis that included faculty from MIT, UB, and Purdue.

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Publications

April 25, 2023

Effective holistic characterization of small molecule effects using heterogeneous biological networks

We enhanced CANDO with multimodal data to better characterize and predict drug behavior.

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December 7, 2021

A Deep-Learning Proteomic-Scale Approach for Drug Design

We enhanced the CANDO platform to enable efficient design of new drugs using principles of multitarget philosophy.

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June 9, 2020

cando.py: Open Source Software for Predictive Bioanalytics of Large Scale Drug–Protein–Disease Data

The engine powering our discovery pipeline is CANDO, an open-source drug discovery platform 15 years in the making.

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Contact

For partnership and collaboration inquiries, please reach out via email.